NACAD antibody (AA 376-425)

Catalog No. ABIN1535054

The Rabbit Polyclonal anti-NACAD antibody (ABIN1535054) specifically detects NACAD in WB and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NACAD antibody (AA 376-425) (ABIN1535054)

Target: NACAD (NAC alpha Domain Containing (NACAD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NACAD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NACAD Antibody

Binding Specificity: AA 376-425

Purpose: NACAD Antibody

Specificity: NACAD Polyclonal Antibody detects endogenous levels of NACAD protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human NACAD. AA range:376-425

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NACAD

Target: NACAD (NAC alpha Domain Containing (NACAD))

Alternative Name: NACAD

Background:

Synonyms: NACAD, KIAA0363, NAC-alpha domain-containing protein 1

Background: function:May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).,similarity:Belongs to the NAC-alpha family.,similarity:Contains 1 NAC-A/B (NAC-alpha/beta) domain.,

Gene Name: NACAD

Protein Name: NAC-alpha domain-containing protein 1

Molecular Weight: 161 kDa

Gene ID: 23148

UniProt: O15069