Nanos Homolog 1 antibody (AA 151-200)

Catalog No. ABIN7226894

The Rabbit Polyclonal anti-Nanos Homolog 1 antibody is suitable to detect Nanos Homolog 1 in samples from Human and Mouse. It has been validated for WB, ELISA and IHC.

Quick Overview for Nanos Homolog 1 antibody (AA 151-200) (ABIN7226894)

Target: Nanos Homolog 1 (NANOS1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nanos Homolog 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Nanos Homolog 1 Antibody

Binding Specificity: AA 151-200

Purpose: Rabbit Anti-Nanos Homologue 1 (NANOS1) Polyclonal Antibody

Specificity: Nanos Homologue 1 (NANOS1) Polyclonal Antibody detects endogenous levels of Nanos Homologue 1 (NANOS1).

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Nanos Homologue 1 (NANOS1) at AA range: 151-200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Nanos Homolog 1

Target: Nanos Homolog 1 (NANOS1)

Alternative Name: Nanos Homologue 1 (NANOS1)

Background: Nanos homolog 1, NOS-1, EC_Rep1aNANOS1 (nanos C2HC-type zinc finger 1) encodes a CCHC-type zinc finger protein that is a member of the nanos family. This protein co-localizes with the RNA-binding protein pumilio RNA-binding family member 2 and may be involved in regulating translation as a post-transcriptional repressor. Mutations in NANOS1 are associated with spermatogenic impairment.

Molecular Weight: 30kD

Gene ID: 340719

UniProt: Q8WY41

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction