NBPF1,9,10,12,14,15,16,20 (AA 700-780) antibody

Catalog No. ABIN7215966

The Rabbit Polyclonal anti-NBPF1,9,10,12,14,15,16,20 antibody (ABIN7215966) specifically detects NBPF1,9,10,12,14,15,16,20 in ELISA, WB, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for NBPF1,9,10,12,14,15,16,20 (AA 700-780) antibody (ABIN7215966)

Target: NBPF1,9,10,12,14,15,16,20

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details

Binding Specificity: AA 700-780

Purpose: Rabbit Anti-NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody

Specificity: NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody detects endogenous levels of NBPF1/9/10/12/14/15/16/20 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human NBPF1/9/10/12/14/15/16/20 at AA range: 700-780

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: NBPF1,9,10,12,14,15,16,20

Alternative Name: NBPF1/9/10/12/14/15/16/20

Background: NBPF12, COAS1, KIAA1245, Neuroblastoma breakpoint family member 12, Chromosome 1 amplified sequence 1, NBPF10, Neuroblastoma breakpoint family member 10, NBPF16, Neuroblastoma breakpoint family member 16, NBPF1, KIAA1693, Neuroblastoma breaNBPF1 is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21. , where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes.

Molecular Weight: 36kD

Gene ID: 55672, 400818, 284565

UniProt: Q5TAG4, Q6P3W6, Q5SXJ2, Q3BBV0, Q3BBW0, Q3BBV1, Q8N660, Q5TI25