NDE1 antibody (AA 270-350)

Catalog No. ABIN7229926

This anti-NDE1 antibody is a Rabbit Polyclonal antibody detecting NDE1 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for NDE1 antibody (AA 270-350) (ABIN7229926)

Target: NDE1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NDE1 Antibody

Binding Specificity: AA 270-350

Purpose: NDE1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of NDE1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human NDE1 protein at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for NDE1

Target: NDE1

Alternative Name: NDE1

Background: Rabbit Anti-NDE1 Polyclonal Antibody,Nuclear distribution protein nudE homolog 1, NudE,NDE1 (NudE Neurodevelopment Protein 1) encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic.,NDE1

Molecular Weight: observerd band 38kDa

Gene ID: 54820

UniProt: Q9NXR1