Necdin-Like 2 antibody (AA 110-190)

Catalog No. ABIN7229550

This Rabbit Polyclonal antibody specifically detects Necdin-Like 2 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Necdin-Like 2 antibody (AA 110-190) (ABIN7229550)

Target: Necdin-Like 2 (NDNL2)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Necdin-Like 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Necdin-Like 2 Antibody

Binding Specificity: AA 110-190

Purpose: Rabbit Anti-MAGG1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MAGG1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MAGG1 protein at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Necdin-Like 2

Target: Necdin-Like 2 (NDNL2)

Alternative Name: MAGG1

Background: Non-structural maintenance of chromosomes element 3 homolog, Non-SMC element 3 homolog, Hepatocellular carcinoma-associated protein 4, MAGE-G1 antigen, Melanoma-associated antigen G1, Necdin-like protein 2The protein encoded by NSMCE3 (NSE3 Homolog, SMC5-SMC6 Complex Component) is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. NSMCE3 is a Protein Coding gene. Diseases associated with NSMCE3 include Lung Disease, Immunodeficiency, And Chromosome Breakage Syndrome and Viral Pneumonia. Among its related pathways are SUMOylation and p75 (NTR) -mediated signaling. An important paralog of NSMCE3 is MAGEF1.

Molecular Weight: 33kD

Gene ID: 56160

UniProt: Q96MG7