nectin-3 antibody (Internal Region)

Catalog No. ABIN7218058

The Rabbit Polyclonal anti-nectin-3 antibody (ABIN7218058) specifically detects nectin-3 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for nectin-3 antibody (Internal Region) (ABIN7218058)

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This nectin-3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-nectin-3 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-Nectin 3 Polyclonal Antibody

Specificity: Nectin 3 Polyclonal Antibody detects endogenous levels of Nectin 3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Nectin 3

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for nectin-3

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Alternative Name: Nectin 3

Background: PVRL3, PRR3, Poliovirus receptor-related protein 3, CDw113, Nectin-3, CD113NECTIN3 encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.

Molecular Weight: 60kD

Gene ID: 25945

UniProt: Q9NQS3

Pathways: Cell-Cell Junction Organization