NPHP4 antibody (AA 850-930)

Catalog No. ABIN7220970

The Rabbit Polyclonal anti-NPHP4 antibody (ABIN7220970) specifically detects NPHP4 in ELISA, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for NPHP4 antibody (AA 850-930) (ABIN7220970)

Target: NPHP4 (Nephronophthisis 4 (NPHP4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPHP4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-NPHP4 Antibody

Binding Specificity: AA 850-930

Purpose: Rabbit Anti-Nephrocystin-4 Polyclonal Antibody

Specificity: Nephrocystin-4 Polyclonal Antibody detects endogenous levels of Nephrocystin-4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Nephrocystin-4 at AA range: 850-930

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NPHP4

Target: NPHP4 (Nephronophthisis 4 (NPHP4))

Alternative Name: Nephrocystin-4

Background: NPHP4, KIAA0673, Nephrocystin-4, NephroretininNPHP4 encodes a protein involved in renal tubular development and function. Nephrocystin-4 interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants.

Gene ID: 261734

UniProt: O75161