NET1 antibody (AA 230-310)

Catalog No. ABIN7227362

The Rabbit Polyclonal anti-NET1 antibody (ABIN7227362) specifically detects NET1 in ELISA and WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for NET1 antibody (AA 230-310) (ABIN7227362)

Target: NET1 (Neuroepithelial Cell Transforming 1 (NET1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NET1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-NET1 Antibody

Binding Specificity: AA 230-310

Purpose: Rabbit Anti-ARHG8 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ARHG8 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ARHG8 protein at AA range: 230-310

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NET1

Target: NET1 (Neuroepithelial Cell Transforming 1 (NET1))

Alternative Name: ARHG8

Background: Neuroepithelial cell-transforming gene 1 protein, Proto-oncogene p65 Net1, Rho guanine nucleotide exchange factor 8NET1 (Neuroepithelial Cell Transforming 1) is a Protein Coding gene. Diseases associated with NET1 include Breast Cancer. Among its related pathways are p75 NTR receptor-mediated signalling and Phospholipase-C Pathway. NET1 is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by NET1 interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of NET1 are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Molecular Weight: 65kD

Gene ID: 10276

UniProt: Q7Z628

Pathways: Neurotrophin Signaling Pathway