Neuroligin 1 antibody (AA 410-490)

Catalog No. ABIN7230024

The Rabbit Polyclonal anti-Neuroligin 1 antibody is suitable to detect Neuroligin 1 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for Neuroligin 1 antibody (AA 410-490) (ABIN7230024)

Target: Neuroligin 1 (NLGN1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuroligin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Neuroligin 1 Antibody

Binding Specificity: AA 410-490

Purpose: Rabbit Anti-NLGN1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of NLGN1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NLGN1 protein at AA range: 410-490

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Neuroligin 1

Target: Neuroligin 1 (NLGN1)

Alternative Name: NLGN1

Background: Neuroligin-1NLGN1 (Neuroligin 1) is a Protein Coding gene. Diseases associated with NLGN1 include Epilepsy, Familial Temporal Lobe, 3 and Corneal Granular Dystrophy. Among its related pathways are Ectoderm Differentiation and Cell adhesion molecules (CAMs). NLGN1 encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses.

Molecular Weight: 92kD

Gene ID: 22871

UniProt: Q8N2Q7

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis