Neuromedin B antibody (AA 20-100)

Catalog No. ABIN7230032

The Rabbit Polyclonal anti-Neuromedin B antibody is suitable to detect Neuromedin B in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for Neuromedin B antibody (AA 20-100) (ABIN7230032)

Target: Neuromedin B

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuromedin B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Neuromedin B Antibody

Binding Specificity: AA 20-100

Purpose: Rabbit Anti-NMB Polyclonal Antibody

Specificity: The antibody detects endogenous levels of NMB protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NMB protein at AA range: 20-100

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Neuromedin B

Target: Neuromedin B

Alternative Name: NMB

Background: Neuromedin-BNMB (Neuromedin B) is a Protein Coding gene. Diseases associated with NMB include Gastrinoma and Neuronal Ceroid Lipofuscinosis. Among its related pathways are Signaling by GPCR and RET signaling. NMB encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of NMB may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants.

Molecular Weight: 13kD

Gene ID: 4828

UniProt: P08949