NAV3 antibody (AA 430-510)

Catalog No. ABIN7229906

The Rabbit Polyclonal anti-NAV3 antibody is suitable to detect NAV3 in samples from Mouse and Human. It has been validated for IF and IHC.

Quick Overview for NAV3 antibody (AA 430-510) (ABIN7229906)

Target: NAV3 (Neuron Navigator 3 (NAV3))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAV3 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-NAV3 Antibody

Binding Specificity: AA 430-510

Purpose: Rabbit Anti-NAV3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of NAV3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NAV3 protein at AA range: 430-510

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NAV3

Target: NAV3 (Neuron Navigator 3 (NAV3))

Alternative Name: NAV3

Background: Neuron navigator 3, Pore membrane and/or filament-interacting-like protein 1, Steerin-3, Unc-53 homolog 3, unc53H3NAV3 (Neuron Navigator 3) is a Protein Coding gene. Diseases associated with NAV3 include Subcutaneous Panniculitis-Like T-Cell Lymphoma. NAV3 belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. NAV3 is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. Multiple alternatively spliced transcript variants for NAV3 have been described but only one has had its full-length nature determined.

Molecular Weight: 262kD

Gene ID: 89795

UniProt: Q8IVL0