ACHB3 antibody (AA 160-240)

Catalog No. ABIN7227174

The Rabbit Polyclonal anti-ACHB3 antibody is suitable to detect ACHB3 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for ACHB3 antibody (AA 160-240) (ABIN7227174)

Target: ACHB3 (LOC101456006) (Neuronal Acetylcholine Receptor Subunit alpha-2 (LOC101456006))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACHB3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ACHB3 Antibody

Binding Specificity: AA 160-240

Purpose: Rabbit Anti-ACHB3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ACHB3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ACHB3 protein at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ACHB3

Target: ACHB3 (LOC101456006) (Neuronal Acetylcholine Receptor Subunit alpha-2 (LOC101456006))

Alternative Name: ACHB3

Background: Neuronal acetylcholine receptor subunit beta-3CHRNB3 (Cholinergic Receptor Nicotinic Beta 3 Subunit) is a Protein Coding gene. Diseases associated with CHRNB3 include Duane Retraction Syndrome and Autosomal Dominant Nocturnal Frontal Lobe Epilepsy. Among its related pathways are Nanog in Mammalian ESC Pluripotency and Acetylcholine Binding And Downstream Events. The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero) pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel.

Molecular Weight: 50kD

Gene ID: 1142

UniProt: Q05901