NPW antibody (AA 90-170)

Catalog No. ABIN7230092

The Rabbit Polyclonal anti-NPW antibody is suitable to detect NPW in samples from Human and Rat. It has been validated for WB and ELISA.

Quick Overview for NPW antibody (AA 90-170) (ABIN7230092)

Target: NPW (Neuropeptide W (NPW))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPW antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NPW Antibody

Binding Specificity: AA 90-170

Purpose: Rabbit Anti-NPW Polyclonal Antibody

Specificity: The antibody detects endogenous levels of NPW protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NPW protein at AA range: 90-170

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NPW

Target: NPW (Neuropeptide W (NPW))

Alternative Name: NPW

Background: Neuropeptide W, Preproprotein L8, hPPL8NPW (Neuropeptide W) is a Protein Coding gene. Diseases associated with NPW include Neurodegeneration With Brain Iron Accumulation 6 and Retinitis Pigmentosa, X-Linked Recessive, 6. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. The product of NPW is processed into 23- and 30-amino acid neuropeptides that bind and activate two G-protein coupled receptors in the central nervous system. The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the adenylate cyclase/protein kinase A signaling cascade.

Molecular Weight: 18kD

Gene ID: 283869

UniProt: Q8N729

Pathways: Feeding Behaviour