NPY1R antibody (AA 190-270)

Catalog No. ABIN7222812

This Rabbit Polyclonal antibody specifically detects NPY1R in WB, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NPY1R antibody (AA 190-270) (ABIN7222812)

Target: NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPY1R antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-NPY1R Antibody

Binding Specificity: AA 190-270

Purpose: NPY1-R Polyclonal Antibody

Specificity: NPY1-R Polyclonal Antibody detects endogenous levels of NPY1-R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human NPY1-R at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for NPY1R

Target: NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))

Alternative Name: NPY1-R

Background: Rabbit Anti-NPY1-R Polyclonal Antibody,NPY1R, NPYR, NPYY1, Neuropeptide Y receptor type 1, NPY1-R,NPY1R belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity.,Neuropeptide Y receptor type 1

Molecular Weight: observerd band 48kDa

Gene ID: 4886

UniProt: P25929

Pathways: Negative Regulation of Hormone Secretion, Feeding Behaviour