NPY5R antibody (AA 190-270)

Catalog No. ABIN7216128

This Rabbit Polyclonal antibody specifically detects NPY5R in WB, IF, ELISA and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NPY5R antibody (AA 190-270) (ABIN7216128)

Target: NPY5R (Neuropeptide Y Receptor Y5 (NPY5R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPY5R antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NPY5R Antibody

Binding Specificity: AA 190-270

Purpose: NPY5-R Polyclonal Antibody

Specificity: NPY5-R Polyclonal Antibody detects endogenous levels of NPY5-R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human NPY5-R at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for NPY5R

Target: NPY5R (Neuropeptide Y Receptor Y5 (NPY5R))

Alternative Name: NPY5-R

Background: Rabbit Anti-NPY5-R Polyclonal Antibody,NPY5R, NPYR5, Neuropeptide Y receptor type 5, NPY5-R, NPY-Y5 receptor, NPYY5-R, Y5 receptor,Neuropeptide Y receptor Y5 encoded by NPY5R is a receptor for neuropeptide Y and peptide YY. Neuropeptide Y receptor Y5 appears to be involved in regulating food intake, with defects in NPY5R being associated with eating disorders. Also, neuropeptide Y receptor Y5 is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for NPY5R.,Neuropeptide Y receptor type 5

Molecular Weight: observerd band 48kDa

Gene ID: 4889

UniProt: Q15761

Pathways: Feeding Behaviour