NIPBL antibody (AA 560-640)

Catalog No. ABIN7230008

This Rabbit Polyclonal antibody specifically detects NIPBL in IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for NIPBL antibody (AA 560-640) (ABIN7230008)

Target: NIPBL (Nipped-B like Protein (NIPBL))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NIPBL antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NIPBL Antibody

Binding Specificity: AA 560-640

Purpose: NIPBL Polyclonal Antibody

Specificity: The antibody detects endogenous levels of NIPBL protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human NIPBL protein at AA range: 560-640

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:300).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for NIPBL

Target: NIPBL (Nipped-B like Protein (NIPBL))

Alternative Name: NIPBL

Background: Rabbit Anti-NIPBL Polyclonal Antibody,Nipped-B-like protein, Delangin, SCC2 homolog,NIPBL (NIPBL, Cohesin Loading Factor) is a Protein Coding gene. Diseases associated with NIPBL include Cornelia De Lange Syndrome 1 and Nipbl-Related Cornelia De Lange Syndrome. Among its related pathways are Cell Cycle, Mitotic and Mitotic Telophase/Cytokinesis. NIPBL encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation.,NIPBL

Molecular Weight: observerd band 308kDa

Gene ID: 25836

UniProt: Q6KC79

Pathways: Sensory Perception of Sound, Stem Cell Maintenance