Nkx2-2 antibody

Catalog No. ABIN7230018

The Rabbit Polyclonal anti-Nkx2-2 antibody has been validated for WB and ELISA. It is suitable to detect Nkx2-2 in samples from Human and Mouse.

Quick Overview for Nkx2-2 antibody (ABIN7230018)

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nkx2-2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Nkx2-2 Antibody

Purpose: NKX22 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of NKX22 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human NKX22 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Nkx2-2

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Alternative Name: NKX22

Background: Rabbit Anti-NKX22 Polyclonal Antibody,Homeobox protein Nkx-2.2, Homeobox protein NK-2 homolog B,NKX2-2 (NK2 Homeobox 2) is a Protein Coding gene. Diseases associated with NKX2-2 include Maturity-Onset Diabetes Of The Young and Oligodendroglioma. Among its related pathways are Regulation of beta-cell development and Dopaminergic Neurogenesis. The protein encoded by NKX2-2 contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. NKX2-2 is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.,NKX22

Molecular Weight: observerd band 30kDa

Gene ID: 4821

UniProt: O95096

Pathways: Dopaminergic Neurogenesis