NKX6-1 antibody (AA 180-260)

Catalog No. ABIN7222772

The Rabbit Polyclonal anti-NKX6-1 antibody (ABIN7222772) specifically detects NKX6-1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NKX6-1 antibody (AA 180-260) (ABIN7222772)

Target: NKX6-1 (NK6 Homeobox 1 (NKX6-1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKX6-1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NKX6-1 Antibody

Binding Specificity: AA 180-260

Purpose: Rabbit Anti-Nkx-6.1 Polyclonal Antibody

Specificity: Nkx-6.1 Polyclonal Antibody detects endogenous levels of Nkx-6.1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Nkx-6.1 at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NKX6-1

Target: NKX6-1 (NK6 Homeobox 1 (NKX6-1))

Alternative Name: Nkx-6).1

Background: NKX6-1, NKX6A, Homeobox protein Nkx-6.1, Homeobox protein NK-6 homolog AIn the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al.

Gene ID: 4825

UniProt: P78426

Pathways: Dopaminergic Neurogenesis, Positive Regulation of Peptide Hormone Secretion