NFE2L3 antibody (AA 460-540)

Catalog No. ABIN7216134

This Rabbit Polyclonal antibody specifically detects NFE2L3 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for NFE2L3 antibody (AA 460-540) (ABIN7216134)

Target: NFE2L3 (Nuclear Factor (erythroid-Derived 2)-Like 3 (NFE2L3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFE2L3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NFE2L3 Antibody

Binding Specificity: AA 460-540

Purpose: Nrf3 Polyclonal Antibody

Specificity: Nrf3 Polyclonal Antibody detects endogenous levels of Nrf3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Nrf3 at AA range: 460-540

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for NFE2L3

Target: NFE2L3 (Nuclear Factor (erythroid-Derived 2)-Like 3 (NFE2L3))

Alternative Name: Nrf3

Background: Rabbit Anti-Nrf3 Polyclonal Antibody,NFE2L3, NRF3, Nuclear factor erythroid 2-related factor 3, NF-E2-related factor 3, NFE2-related factor 3, Nuclear factor, erythroid derived 2, like 3,NFE2L3 encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. Nuclear factor, erythroid 2 like 3 heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. Nuclear factor, erythroid 2 like 3 is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of NFE2L3 are found on chromosomes 16, 17, and 18.,Nuclear factor erythroid 2-related factor 3

Molecular Weight: observerd band 75kDa

Gene ID: 9603

UniProt: Q9Y4A8