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NFE2L3 antibody (C-Term)

NFE2L3 Reactivity: Human WB Host: Rabbit Polyclonal RB41576 unconjugated
Catalog No. ABIN1881578
  • Target See all NFE2L3 Antibodies
    NFE2L3 (Nuclear Factor (erythroid-Derived 2)-Like 3 (NFE2L3))
    Binding Specificity
    • 12
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 666-694, C-Term
    Reactivity
    • 30
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 30
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NFE2L3 antibody is un-conjugated
    Application
    • 20
    • 18
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This NFE2L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 666-694 amino acids from the C-terminal region of human NFE2L3.
    Clone
    RB41576
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

    Zhang, Kobayashi, Yamamoto, Hayes: "The Nrf3 transcription factor is a membrane-bound glycoprotein targeted to the endoplasmic reticulum through its N-terminal homology box 1 sequence." in: The Journal of biological chemistry, Vol. 284, Issue 5, pp. 3195-210, (2009) (PubMed).

    Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

  • Target
    NFE2L3 (Nuclear Factor (erythroid-Derived 2)-Like 3 (NFE2L3))
    Alternative Name
    NFE2L3 (NFE2L3 Products)
    Synonyms
    NRF3 antibody, Nrf3 antibody, nuclear factor, erythroid 2 like 3 antibody, nuclear factor, erythroid derived 2, like 3 antibody, nuclear factor, erythroid 2-like 3 antibody, NFE2L3 antibody, Nfe2l3 antibody
    Background
    This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.
    Molecular Weight
    76154
    NCBI Accession
    NP_004280
    UniProt
    Q9Y4A8
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