CAMKK2 antibody (AA 501-588) (Biotin)

Catalog No. ABIN716428

This Rabbit Polyclonal antibody specifically detects CAMKK2 in WB, IHC (p) and IHC (fro). It exhibits reactivity toward Human, Mouse, Rat, Pig and Sheep.

Quick Overview for CAMKK2 antibody (AA 501-588) (Biotin) (ABIN716428)

Target: CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))

Reactivity: Human, Mouse, Rat, Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAMKK2 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CAMKK2 Antibody (Biotin)

Binding Specificity: AA 501-588

Cross-Reactivity: Human, Mouse, Pig, Rat, Sheep

Predicted Reactivity: Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CAMKK2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CAMKK2

Target: CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))

Alternative Name: Camkk2

Background:

Synonyms: Calcium/calmodulin dependent protein kinase beta, Calcium/calmodulin dependent protein kinase kinase 2, Calcium/calmodulin dependent protein kinase kinase beta, CaM kinase kinase beta, CaM KK beta, CAMKK 2, CAMKK, CaMKK beta, CAMKK beta protein, CAMKKB.

Background: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Seven transcript variants encoding six distinct isoforms have been identified for this gene. Additional splice variants have been described but their full-length nature has not been determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases. [provided by RefSeq, Jul 2008].

Gene ID: 10645

Pathways: AMPK Signaling