HCRTR1 antibody (AA 270-350)

Catalog No. ABIN7221468

This Rabbit Polyclonal antibody specifically detects HCRTR1 in ELISA and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for HCRTR1 antibody (AA 270-350) (ABIN7221468)

Target: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCRTR1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-HCRTR1 Antibody

Binding Specificity: AA 270-350

Purpose: Rabbit Anti-Orexin R-1 Polyclonal Antibody

Specificity: Orexin R-1 Polyclonal Antibody detects endogenous levels of Orexin R-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Orexin R-1 at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HCRTR1

Target: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Alternative Name: Orexin R-1

Background: HCRTR1, Orexin receptor type 1, Ox-1-R, Ox1-R, Ox1R, Hypocretin receptor type 1The hypocretin receptor 1 encoded by HCRTR1 is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.

Gene ID: 3061

UniProt: O43613

Pathways: Feeding Behaviour