ORC4 antibody (AA 140-220)

Catalog No. ABIN7230406

The Rabbit Polyclonal anti-ORC4 antibody (ABIN7230406) specifically detects ORC4 in ELISA and WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ORC4 antibody (AA 140-220) (ABIN7230406)

Target: ORC4 (Origin Recognition Complex, Subunit 4 (ORC4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-ORC4 Antibody

Binding Specificity: AA 140-220

Purpose: Rabbit Anti-ORC4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ORC4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ORC4 protein at AA range: 140-220

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ORC4

Target: ORC4 (Origin Recognition Complex, Subunit 4 (ORC4))

Alternative Name: ORC4

Background: Origin recognition complex subunit 4ORC4 (Origin Recognition Complex Subunit 4) is a Protein Coding gene. Diseases associated with ORC4 include Meier-Gorlin Syndrome 2 and Mbd5 Haploinsufficiency. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and E2F mediated regulation of DNA replication.

Molecular Weight: 47kD

Gene ID: 5000

UniProt: O43929

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA