ORC5 antibody

Catalog No. ABIN7230408

This Rabbit Polyclonal antibody specifically detects ORC5 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for ORC5 antibody (ABIN7230408)

Target: ORC5 (Origin Recognition Complex, Subunit 5 (ORC5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ORC5 Antibody

Purpose: Rabbit Anti-ORC5 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ORC5 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ORC5 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ORC5

Target: ORC5 (Origin Recognition Complex, Subunit 5 (ORC5))

Alternative Name: ORC5

Background: Origin recognition complex subunit 5The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. Origin Recognition Complex Subunit 5 encoded by ORC5 is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Molecular Weight: 47kD

Gene ID: 5001

UniProt: O43913

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA