OAZ2 antibody (AA 90-170)

Catalog No. ABIN7230184

The Rabbit Polyclonal anti-OAZ2 antibody is suitable to detect OAZ2 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for OAZ2 antibody (AA 90-170) (ABIN7230184)

Target: OAZ2 (Ornithine Decarboxylase Antizyme 2 (OAZ2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OAZ2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-OAZ2 Antibody

Binding Specificity: AA 90-170

Purpose: Rabbit Anti-OAZ2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of OAZ2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human OAZ2 protein at AA range: 90-170

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for OAZ2

Target: OAZ2 (Ornithine Decarboxylase Antizyme 2 (OAZ2))

Alternative Name: OAZ2

Background: Ornithine decarboxylase antizyme 2, AZ2, ODC-Az 2OAZ2 (Ornithine Decarboxylase Antizyme 2) is a Protein Coding gene. Among its related pathways are Metabolism and CDK-mediated phosphorylation and removal of Cdc6. The protein encoded by OAZ2 belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamines. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis, thus, completing the auto-regulatory circuit.

Molecular Weight: 20kD

Gene ID: 4947

UniProt: O95190