Osteoactivin antibody

Catalog No. ABIN7228728

This anti-Osteoactivin antibody is a Rabbit Polyclonal antibody detecting Osteoactivin in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for Osteoactivin antibody (ABIN7228728)

Target: Osteoactivin (GPNMB)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Osteoactivin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Osteoactivin Antibody

Purpose: GPNMB Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GPNMB protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human GPNMB protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Osteoactivin

Target: Osteoactivin (GPNMB)

Alternative Name: GPNMB

Background: Rabbit Anti-GPNMB Polyclonal Antibody,Transmembrane glycoprotein HGFIN,The protein encoded by GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for GPNMB.,GPNMB

Molecular Weight: observerd band 62kDa

Gene ID: 10457

UniProt: Q14956