OXGR1 antibody (AA 130-210)

Catalog No. ABIN7230432

This Rabbit Polyclonal antibody specifically detects OXGR1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for OXGR1 antibody (AA 130-210) (ABIN7230432)

Target: OXGR1 (Oxoglutarate (Alpha-Ketoglutarate) Receptor 1 (OXGR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OXGR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-OXGR1 Antibody

Binding Specificity: AA 130-210

Purpose: OXGR1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of OXGR1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human OXGR1 protein at AA range: 130-210

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for OXGR1

Target: OXGR1 (Oxoglutarate (Alpha-Ketoglutarate) Receptor 1 (OXGR1))

Alternative Name: OXGR1

Background: Rabbit Anti-OXGR1 Polyclonal Antibody,2-oxoglutarate receptor 1, Alpha-ketoglutarate receptor 1, G-protein coupled receptor 80, G-protein coupled receptor 99, P2Y purinoceptor 15, P2Y15, P2Y-like GPCR, P2Y-like nucleotide receptor,OXGR1 encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily. The encoded protein is activated by the citric acid intermediate, oxoglutarate, as well as several cysteinyl leukotrienes, including leukotrienes E4, C4 and D4, which are implicated in many inflammatory disorders. In mice, a knock-out of OXGR1 leads to middle ear inflammation, changes in the mucosal epithelium, and an increase in fluid behind the eardrum, and is associated with hearing loss. Alternative splicing results in multiple transcript variants.,OXGR1

Molecular Weight: observerd band 37kDa

Gene ID: 27199

UniProt: Q96P68