POR antibody
Quick Overview for POR antibody (ABIN7229924)
Target
See all POR AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- NCPR Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of NCPR protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human NCPR protein
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- POR (P450 (Cytochrome) Oxidoreductase (POR))
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Alternative Name
- NCPR
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Background
- Rabbit Anti-NCPR Polyclonal Antibody,NADPH--cytochrome P450 reductase, CPR, P450R,POR encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. Cytochrome P450 Oxidoreductase binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.,NCPR
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Molecular Weight
- observerd band 74kDa
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Gene ID
- 5447
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UniProt
- P16435
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Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interactome
Target
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