PAX1 antibody (Internal Region)

Catalog No. ABIN7222938

This Rabbit Polyclonal antibody specifically detects PAX1 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for PAX1 antibody (Internal Region) (ABIN7222938)

Target: PAX1 (Paired Box 1 (PAX1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PAX1 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-Pax-1 Polyclonal Antibody

Specificity: Pax-1 Polyclonal Antibody detects endogenous levels of Pax-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Pax-1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PAX1

Target: PAX1 (Paired Box 1 (PAX1))

Alternative Name: Pax-1

Background: PAX1, HUP48, Paired box protein Pax-1, HuP48PAX1 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. PAX1 plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. PAX1 is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations.

Molecular Weight: 36kD

Gene ID: 5075

UniProt: P15863