PPT1 antibody (N-Term)

Catalog No. ABIN7223418

This anti-PPT1 antibody is a Rabbit Polyclonal antibody detecting PPT1 in ELISA and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for PPT1 antibody (N-Term) (ABIN7223418)

Target: PPT1 (Palmitoyl-Protein Thioesterase 1 (PPT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPT1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PPT1 Antibody

Binding Specificity: N-Term

Purpose: CLN1 Polyclonal Antibody

Specificity: CLN1 Polyclonal Antibody detects endogenous levels of CLN1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human CLN1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PPT1

Target: PPT1 (Palmitoyl-Protein Thioesterase 1 (PPT1))

Alternative Name: CLN1

Background: Rabbit Anti-CLN1 Polyclonal Antibody,PPT1, PPT, Palmitoyl-protein thioesterase 1, PPT-1, Palmitoyl-protein hydrolase 1,The protein encoded by PPT1 (palmitoyl-protein thioesterase 1) is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in PPT1 are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for PPT1.,Palmitoyl-protein thioesterase 1

Molecular Weight: observerd band 37kDa

Gene ID: 5538

UniProt: P50897

Pathways: SARS-CoV-2 Protein Interactome