PPT1 antibody (AA 1-306)

Catalog No. ABIN1944801

Cited in 3+ publications. The Mouse Monoclonal anti-PPT1 antibody (Clone 1117CT11-2-1-4) (ABIN1944801) specifically detects PPT1 in WB, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for PPT1 antibody (AA 1-306) (ABIN1944801)

Target: PPT1 (Palmitoyl-Protein Thioesterase 1 (PPT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PPT1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1117CT11-2-1-4

Product Details anti-PPT1 Antibody

Binding Specificity: AA 1-306

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This PPT1 antibody is generated from a mouse immunized with a full-length recombinant protein from human PPT1.

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:25. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-PPT1 antibody (ABIN1944801)

Crews, Lane, Schreiber: "Didemnin binds to the protein palmitoyl thioesterase responsible for infantile neuronal ceroid lipofuscinosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 9, pp. 4316-9, (1996) (PubMed).

Schriner, Yi, Hofmann: "cDNA and genomic cloning of human palmitoyl-protein thioesterase (PPT), the enzyme defective in infantile neuronal ceroid lipofuscinosis." in: Genomics, Vol. 34, Issue 3, pp. 317-22, (1996) (PubMed).

Vesa, Hellsten, Verkruyse, Camp, Rapola, Santavuori, Hofmann, Peltonen: "Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis." in: Nature, Vol. 376, Issue 6541, pp. 584-7, (1995) (PubMed).

Target Details for PPT1

Target: PPT1 (Palmitoyl-Protein Thioesterase 1 (PPT1))

Alternative Name: PPT1

Background: Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.

Molecular Weight: 34193

Gene ID: 5538

UniProt: P50897

Pathways: SARS-CoV-2 Protein Interactome