PON2 antibody

Catalog No. ABIN7230728

This Rabbit Polyclonal antibody specifically detects PON2 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PON2 antibody (ABIN7230728)

Target: PON2 (Paraoxonase 2 (PON2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PON2 Antibody

Purpose: Rabbit Anti-PON2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PON2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PON2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PON2

Target: PON2 (Paraoxonase 2 (PON2))

Alternative Name: PON2

Background: Aromatic esterase 2, A-esterase 2, Serum aryldialkylphosphatase 2PON2 encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in PON2 may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

Molecular Weight: 38kD

Gene ID: 5445

UniProt: Q15165