PCF11 antibody (AA 490-570)

Catalog No. ABIN7230522

This Rabbit Polyclonal antibody specifically detects PCF11 in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for PCF11 antibody (AA 490-570) (ABIN7230522)

Target: PCF11 (PCF11, Cleavage and Polyadenylation Factor Subunit (PCF11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCF11 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-PCF11 Antibody

Binding Specificity: AA 490-570

Purpose: Rabbit Anti-PCF11 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PCF11 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PCF11 protein at AA range: 490-570

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PCF11

Target: PCF11 (PCF11, Cleavage and Polyadenylation Factor Subunit (PCF11))

Alternative Name: PCF11

Background: Pre-mRNA cleavage complex 2 protein Pcf11, Pre-mRNA cleavage complex II protein Pcf11PCF11 (PCF11 Cleavage And Polyadenylation Factor Subunit) is a Protein Coding gene. Among its related pathways are mRNA surveillance pathway and Formation of HIV elongation complex in the absence of HIV Tat. The protein encoded by PCF11 binds to CLP1 to form pre-mRNA cleavage factor IIm. The encoded protein is necessary for efficient Pol II transcription termination and may be involved in degradation of the 3' product of polyA site cleavage.

Molecular Weight: 171kD

Gene ID: 51585

UniProt: O94913