PTX3 antibody (AA 10-90)

Catalog No. ABIN7216702

The Rabbit Polyclonal anti-PTX3 antibody is suitable to detect PTX3 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for PTX3 antibody (AA 10-90) (ABIN7216702)

Target: PTX3 (Pentraxin 3 (PTX3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PTX3 Antibody

Binding Specificity: AA 10-90

Purpose: Rabbit Anti-Ptx3 Polyclonal Antibody

Specificity: Ptx3 Polyclonal Antibody detects endogenous levels of Ptx3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Ptx3 at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PTX3

Target: PTX3 (Pentraxin 3 (PTX3))

Alternative Name: Ptx3

Background: PTX3, TNFAIP5, TSG14, Pentraxin-related protein PTX3, Pentaxin-related protein PTX3, Tumor necrosis factor alpha-induced protein 5, TNF alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14PTX3 encodes a member of the pentraxin protein family. The expression of pentraxin 3 is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. Pentraxin 3 promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. Pentraxin 3 serves as a biomarker for several inflammatory conditions.

Molecular Weight: 40kD

Gene ID: 5806

UniProt: P26022