PER3 antibody (AA 40-120)

Catalog No. ABIN7225692

The Rabbit Polyclonal anti-PER3 antibody (ABIN7225692) specifically detects PER3 in WB, ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PER3 antibody (AA 40-120) (ABIN7225692)

Target: PER3 (Period Homolog 3 (PER3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PER3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PER3 Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-Per3 Polyclonal Antibody

Specificity: Per3 Polyclonal Antibody detects endogenous levels of Per3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Per3 at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PER3

Target: PER3 (Period Homolog 3 (PER3))

Alternative Name: Per3

Background: PER3, GIG13, Period circadian protein homolog 3, hPER3, Cell growth-inhibiting gene 13 protein, Circadian clock protein PERIOD 3PER3 (period circadian clock 3) is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. PER3 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in PER3 have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for PER3.

Molecular Weight: 130kD

Gene ID: 8863

UniProt: P56645