PMP22 antibody (AA 80-160)

Catalog No. ABIN7223218

The Rabbit Polyclonal anti-PMP22 antibody is suitable to detect PMP22 in samples from Human, Rat and Mouse. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for PMP22 antibody (AA 80-160) (ABIN7223218)

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PMP22 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-PMP22 Antibody

Binding Specificity: AA 80-160

Purpose: Rabbit Anti-GAS3 Polyclonal Antibody

Specificity: GAS3 Polyclonal Antibody detects endogenous levels of GAS3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human GAS3 at AA range: 80-160

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PMP22

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Alternative Name: GAS3

Background: PMP22, GAS3, Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, GAS-3PMP22 (peripheral myelin protein 22) encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of PMP22 are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants.

Molecular Weight: 22kD

Gene ID: 5376

UniProt: Q01453