PEX14 antibody

Catalog No. ABIN7230594

The Rabbit Polyclonal anti-PEX14 antibody is suitable to detect PEX14 in samples from Human, Mouse and Rat. It has been validated for WB and IHC.

Quick Overview for PEX14 antibody (ABIN7230594)

Target: PEX14 (Peroxisomal Biogenesis Factor 14 (PEX14))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX14 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PEX14 Antibody

Purpose: Rabbit Anti-PEX14 Polyclonal Antibody

Specificity: This antibody detects endogenous levels of PEX14.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PEX14 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PEX14

Target: PEX14 (Peroxisomal Biogenesis Factor 14 (PEX14))

Alternative Name: PEX14

Background: Peroxisomal membrane protein PEX14, PTS1 receptor-docking protein, Peroxin-14, Peroxisomal membrane anchor protein PEX14PEX14 encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in PEX14 results in one form of Zellweger syndrome.

Molecular Weight: 41kD

Gene ID: 5195

UniProt: O75381

Pathways: Maintenance of Protein Location