PEX3 antibody (AA 30-110)

Catalog No. ABIN7216506

This anti-PEX3 antibody is a Rabbit Polyclonal antibody detecting PEX3 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for PEX3 antibody (AA 30-110) (ABIN7216506)

Target: PEX3 (Peroxisomal Biogenesis Factor 3 (PEX3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PEX3 Antibody

Binding Specificity: AA 30-110

Purpose: Peroxin 3 Polyclonal Antibody

Specificity: Peroxin 3 Polyclonal Antibody detects endogenous levels of Peroxin 3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Peroxin 3 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PEX3

Target: PEX3 (Peroxisomal Biogenesis Factor 3 (PEX3))

Alternative Name: Peroxin 3

Background: Rabbit Anti-Peroxin 3 Polyclonal Antibody,PEX3, Peroxisomal biogenesis factor 3, Peroxin-3, Peroxisomal assembly protein PEX3,The product of PEX3 is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in PEX3 are a cause Zellweger syndrome (ZWS).,Peroxisomal biogenesis factor 3

Molecular Weight: observerd band 42kDa

Gene ID: 8504

UniProt: P56589