PDE4C antibody (AA 260-340)

Catalog No. ABIN7216476

The Rabbit Polyclonal anti-PDE4C antibody (ABIN7216476) specifically detects PDE4C in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PDE4C antibody (AA 260-340) (ABIN7216476)

Target: PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE4C antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PDE4C Antibody

Binding Specificity: AA 260-340

Purpose: PDE4C Polyclonal Antibody

Specificity: PDE4C Polyclonal Antibody detects endogenous levels of PDE4C protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human PDE4C at AA range: 260-340

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PDE4C

Target: PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))

Alternative Name: PDE4C

Background: Rabbit Anti-PDE4C Polyclonal Antibody,PDE4C, DPDE1, cAMP-specific 3', 5'-cyclic phosphodiesterase 4C, DPDE1, PDE21,Phosphodiesterase 4C encoded by PDE4C belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, phosphodiesterase 4C plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for PDE4C.,cAMP-specific 3',5'-cyclic phosphodiesterase 4C

Molecular Weight: observerd band 80kDa

Gene ID: 5143

UniProt: Q08493

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process