PDE7A antibody

Catalog No. ABIN7230562

The Rabbit Polyclonal anti-PDE7A antibody is suitable to detect PDE7A in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for PDE7A antibody (ABIN7230562)

Target: PDE7A (phosphodiesterase 7A (PDE7A))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE7A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PDE7A Antibody

Purpose: PDE7A Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PDE7A protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human PDE7A protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PDE7A

Target: PDE7A (phosphodiesterase 7A (PDE7A))

Alternative Name: PDE7A

Background: Rabbit Anti-PDE7A Polyclonal Antibody,High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, HCP1, TM22,The protein encoded by PDE7A belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for PDE7A. PDE7A (Phosphodiesterase 7A) is a Protein Coding gene. Diseases associated with PDE7A include Chronic Lymphocytic Leukemia and Low Compliance Bladder. Among its related pathways are G alpha(s) signalling events and Ectoderm Differentiation.,PDE7A

Molecular Weight: observerd band 53kDa

Gene ID: 5150

UniProt: Q13946

Pathways: cAMP Metabolic Process