Phospholipase C beta 2 antibody (Internal Region)

Catalog No. ABIN7223174

The Rabbit Polyclonal anti-Phospholipase C beta 2 antibody (ABIN7223174) specifically detects Phospholipase C beta 2 in WB and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Phospholipase C beta 2 antibody (Internal Region) (ABIN7223174)

Target: Phospholipase C beta 2 (PLCb2) (phospholipase C beta 2 (PLCb2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase C beta 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Phospholipase C beta 2 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-PLC β2 Polyclonal Antibody

Specificity: PLC β2 Polyclonal Antibody detects endogenous levels of PLC β2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human PLC beta2

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Phospholipase C beta 2

Target: Phospholipase C beta 2 (PLCb2) (phospholipase C beta 2 (PLCb2))

Alternative Name: PLC beta2

Background: PLCB2, 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-2, Phosphoinositide phospholipase C-beta-2, Phospholipase C-beta-2, PLC-beta-2PLCB2 (Phospholipase C Beta 2) is a Protein Coding gene. Diseases associated with PLCB2 include prostate leiomyosarcoma. Among its related pathways are cGMP-PKG signaling pathway and African trypanosomiasis. GO annotations related to this gene include calcium ion binding and phosphoric diester hydrolase activity. An important paralog of this gene is PLCB3.

Molecular Weight: 150kD

Gene ID: 5330

UniProt: Q00722

Pathways: WNT Signaling, Thyroid Hormone Synthesis, CXCR4-mediated Signaling Events, G-protein mediated Events, Thromboxane A2 Receptor Signaling