Phospholipase C beta 4 antibody

Catalog No. ABIN7230676

This Rabbit Polyclonal antibody specifically detects Phospholipase C beta 4 in WB and ELISA. It exhibits reactivity toward Human and Rat.

Quick Overview for Phospholipase C beta 4 antibody (ABIN7230676)

Target: Phospholipase C beta 4 (PLCb4)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase C beta 4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Phospholipase C beta 4 Antibody

Purpose: Rabbit Anti-PLCB4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PLCB4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PLCB4 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Phospholipase C beta 4

Target: Phospholipase C beta 4 (PLCb4)

Alternative Name: PLCB4

Background: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4, Phosphoinositide phospholipase C-beta-4, Phospholipase C-beta-4, PLC-beta-4The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina. Multiple transcript variants encoding different isoforms have been found for this gene. The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 129kD

Gene ID: 5332

UniProt: Q15147

Pathways: WNT Signaling, Thyroid Hormone Synthesis, G-protein mediated Events