PLCB3 antibody (pSer1105)

Catalog No. ABIN7213242

The Rabbit Polyclonal anti-PLCB3 antibody is suitable to detect PLCB3 in samples from Human, Rat and Mouse. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for PLCB3 antibody (pSer1105) (ABIN7213242)

Target: PLCB3 (phospholipase C, beta 3 (Phosphatidylinositol-Specific) (PLCB3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLCB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-PLCB3 Antibody

Binding Specificity: pSer1105

Purpose: Rabbit Anti-PLC β3 (phospho Ser1105) Polyclonal Antibody

Specificity: Phospho-PLC β3 (S1105) Polyclonal Antibody detects endogenous levels of PLC β3 protein only when phosphorylated at S1105.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human PLC beta3 Phospho-Ser1105

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PLCB3

Target: PLCB3 (phospholipase C, beta 3 (Phosphatidylinositol-Specific) (PLCB3))

Alternative Name: PLC beta3

Background: PLCB3, 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-3, Phosphoinositide phospholipase C-beta-3, Phospholipase C-beta-3, PLC-beta-3PLCB3 encodes a member (phospholipase C beta 3) of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.

Molecular Weight: 160kD

Gene ID: 5331

UniProt: Q01970

Pathways: WNT Signaling, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, CXCR4-mediated Signaling Events, G-protein mediated Events