PIF1 antibody (AA 150-230)

Catalog No. ABIN7230636

The Rabbit Polyclonal anti-PIF1 antibody (ABIN7230636) specifically detects PIF1 in ELISA and WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PIF1 antibody (AA 150-230) (ABIN7230636)

Target: PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIF1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-PIF1 Antibody

Binding Specificity: AA 150-230

Purpose: Rabbit Anti-PIF1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PIF1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PIF1 protein at AA range: 150-230

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PIF1

Target: PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))

Alternative Name: PIF1

Background: ATP-dependent DNA helicase PIF1, DNA repair and recombination helicase PIF1, PIF1/RRM3 DNA helicase-like proteinPIF1 encodes a DNA-dependent adenosine triphosphate (ATP)-metabolizing enzyme that functions as a 5' to 3' DNA helicase. The encoded protein can resolve G-quadruplex structures and RNA-DNA hybrids at the ends of chromosomes. It also prevents telomere elongation by inhibiting the actions of telomerase. Alternative splicing and the use of alternative start codons results in multiple isoforms that are differentially localized to either the mitochondria or the nucleus.

Molecular Weight: 70kD

Gene ID: 80119

UniProt: Q9H611