PLG antibody (Cleaved-Val98)

Catalog No. ABIN7212540

This Rabbit Polyclonal antibody specifically detects PLG in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PLG antibody (Cleaved-Val98) (ABIN7212540)

Target: PLG (Plasminogen (PLG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLG antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PLG Antibody

Binding Specificity: AA 50-130, Cleaved-Val98

Purpose: Rabbit Anti-Cleaved-Plasminogen HC A short form (V98) Polyclonal Antibody

Specificity: Cleaved-Plasminogen HC A short form (V98) Polyclonal Antibody detects endogenous levels of fragment of activated Plasminogen HC A short form protein resulting from cleavage adjacent to V98.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Plasminogen HC A short form at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PLG

Target: PLG (Plasminogen (PLG))

Alternative Name: Plasminogen HC A short form

Background: PLG, PlasminogenThe protein encoded by PLG is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in PLG are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for PLG.

Molecular Weight: 54kD

Gene ID: 5340

UniProt: P00747

Pathways: Complement System, Lipid Metabolism