PLS1 antibody (AA 170-250)

Catalog No. ABIN7230698

The Rabbit Polyclonal anti-PLS1 antibody (ABIN7230698) specifically detects PLS1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PLS1 antibody (AA 170-250) (ABIN7230698)

Target: PLS1 (Plastin 1 (PLS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PLS1 Antibody

Binding Specificity: AA 170-250

Purpose: Rabbit Anti-PLS1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PLS1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PLS1 protein at AA range: 170-250

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PLS1

Target: PLS1 (Plastin 1 (PLS1))

Alternative Name: PLS1

Background: Phospholipid scramblase 1, PL scramblase 1, Ca(2+)-dependent phospholipid scramblase 1, Erythrocyte phospholipid scramblase, MmTRA1bPLSCR1 (Phospholipid Scramblase 1) is a Protein Coding gene. Diseases associated with PLSCR1 include Scott Syndrome. Among its related pathways are EGF/EGFR Signaling Pathway. May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.

Molecular Weight: 34kD

Gene ID: 5359

UniProt: O15162