PEAR1 antibody (AA 910-990)

Catalog No. ABIN7230580

The Rabbit Polyclonal anti-PEAR1 antibody is suitable to detect PEAR1 in samples from Human and Mouse. It has been validated for ELISA and WB.

Quick Overview for PEAR1 antibody (AA 910-990) (ABIN7230580)

Target: PEAR1 (Platelet Endothelial Aggregation Receptor 1 (PEAR1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEAR1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-PEAR1 Antibody

Binding Specificity: AA 910-990

Purpose: Rabbit Anti-PEAR1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PEAR1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PEAR1 protein at AA range: 910-990

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PEAR1

Target: PEAR1 (Platelet Endothelial Aggregation Receptor 1 (PEAR1))

Alternative Name: PEAR1

Background: Multiple epidermal growth factor-like domains protein 12, Multiple EGF-like domains protein 12PEAR1 (Platelet Endothelial Aggregation Receptor 1) is a Protein Coding gene. Diseases associated with PEAR1 include Sticky Platelet Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. An important paralog of this gene is MEGF10. When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells. PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation.

Molecular Weight: 114kD

Gene ID: 375033

UniProt: Q5VY43