PF4 antibody (AA 51-100)

Catalog No. ABIN7230600

The Rabbit Polyclonal anti-PF4 antibody (ABIN7230600) specifically detects PF4 in WB, IHC and ELISA. The antibody is reactive with Human and Rat samples.

Quick Overview for PF4 antibody (AA 51-100) (ABIN7230600)

Target: PF4 (Platelet Factor 4 (PF4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PF4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PF4 Antibody

Binding Specificity: AA 51-100

Purpose: Rabbit Anti-PF-4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PF-4

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PF-4 protein at AA range: 51-100

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PF4

Target: PF4 (Platelet Factor 4 (PF4))

Alternative Name: PF-4

Background: Platelet factor 4, PF-4, C-X-C motif chemokine 4, Iroplact, Oncostatin-APF-4 encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. PF-4is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. PF4 (Platelet Factor 4) is a Protein Coding gene. Diseases associated with PF4 include Erythromelalgia and Thrombocytopenia. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Akt Signaling.

Gene ID: 5196

UniProt: P02776