PDGFRL antibody (AA 50-130)

Catalog No. ABIN7230606

This Rabbit Polyclonal antibody specifically detects PDGFRL in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PDGFRL antibody (AA 50-130) (ABIN7230606)

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFRL antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PDGFRL Antibody

Binding Specificity: AA 50-130

Purpose: Rabbit Anti-PGFRL Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PGFRL protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PGFRL protein at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PDGFRL

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Alternative Name: PGFRL

Background: Platelet-derived growth factor receptor-like protein, PDGFR-like protein, PDGF receptor beta-like tumor suppressorPDGFRL encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing PDGFRL, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL product may function as a tumor suppressor.

Molecular Weight: 41kD

Gene ID: 5157

UniProt: Q15198

Pathways: Platelet-derived growth Factor Receptor Signaling