PLEC antibody (AA 240-320)
Quick Overview for PLEC antibody (AA 240-320) (ABIN7230686)
Target
See all PLEC AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 240-320
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Purpose
- PLEC Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of PLEC protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human PLEC protein at AA range: 240-320
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:300).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PLEC (Plectin (PLEC))
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Alternative Name
- PLEC
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Background
- Rabbit Anti-PLEC Polyclonal Antibody,Plectin, PCN, PLTN, Hemidesmosomal protein 1, HD1, Plectin-1,PLEC (Plectin) is a Protein Coding gene. Diseases associated with PLEC include Epidermolysis Bullosa Simplex, Ogna Type and Muscular Dystrophy, Limb-Girdle, Type 2Q. Among its related pathways are Cytoskeleton remodeling Neurofilaments and Collagen chain trimerization. PLEC is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton.,PLEC
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Molecular Weight
- observerd band 515kDa
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Gene ID
- 5339
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UniProt
- Q15149
Target
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